Efficacy of combined repetitive transcranial magnetic stimulation and virtual reality versus sham transcranial magnetic stimulation on hand function, grip strength, daily activities, and self efficacy in subacute hemiplegic stroke- a randomized placebo controlled trial

Problem of the study

The study on the efficacy of combined repetitive transcranial magnetic stimulation (rTMS) and virtual reality (VR) exercises in motor recovery, grip strength, activity, and self-efficacy in subacute stroke patients addresses a critical gap in stroke rehabilitation. While individual therapies such as rTMS and VR exercises have shown promise in improving motor function and neuroplasticity, there is limited research on their combined effects in the subacute phase of stroke recovery. This period is crucial for maximizing recovery potential, as patients are often still undergoing significant neural plasticity. The need for this study arises from the potential of combining non-invasive brain stimulation (rTMS) with immersive, task-specific training (VR) to enhance motor recovery more effectively than either intervention alone. By examining outcomes like grip strength, functional activity, and self-efficacy, the study aims to provide insights into how these therapies can work synergistically to improve both physical and psychological aspects of rehabilitation, thereby advancing treatment strategies for subacute stroke patients.