NCT06744946已完成4 期
Comparison Between Pleurodesis by a Combination of Bleomycin and Tranxemic Acid Solution and Thoracoscopic Talc Poudrage in Malignant Pleural Effusion
Mohamed Sabry1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年9月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Dyspnea Borg Scale
研究概览
简要总结
Comparing Two Methods to Treat Fluid Build-up in Chest for Cancer Patients:Talc Powder Surgery versus Chest Tube Medicine.
详细描述
Closure of the space where the effusion is recurrently accumulated through talc poudrage in thoracoscopy or bleomycin - tranxemic acid solution injection in chest tube.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (more than 18 years) with malignant pleural effusion or highly suspected exudate.
- •Fit patients for the procedure selected.
排除标准
- •Inability to provide informed consent for the procedure.
- •Hemodynamically unstable patients.
- •Bleeding diathesis.
- •Uncontrolled cough.
- •Hypoxic index less than
- •Endobronchial obstruction.
- •Pleural thickening with trapped lung.
研究组 & 干预措施
the first arm thoracoscopic talc poudrage and the second arm Bleomycin -Tranxemic mic acid mixture
Experimental
the first arm is talc insufflation through medical thoracoscopy the second arm involve bleomycin- tranxemic acid mixture injection in intercostal tube
干预措施: thoracoscope (Procedure)
结局指标
主要结局
Dyspnea Borg Scale
时间窗: one month
the rate of shortness of breath from number 0 to number 10
次要结局
未报告次要终点
研究者
Mohamed Sabry
Lecturer of chest diseases
Alexandria University
研究点 (1)
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