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临床试验/ISRCTN74386719
ISRCTN74386719已完成不适用

Preventive antibacterial short-term therapy in patients with acute ischemic infarction in the territory of the middle cerebral artery (MCA)

Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)0 个研究点目标入组 80 人开始时间: 2004年7月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • The double blind, randomised and controlled study will be carried out on two groups of about 40 patients each. Since patients with large infarctions in the territory of the middle cerebral artery and a subsequent severe neurological deficit (National Institutes of Health-Stroke-Scale [NIHSS] greater than 11) have the highest risk of pneumonia, we include only this subpopulation of stroke patients in our study.
  • 1. Severe ischemic strokes in MCA territory (area greater than 50% in cerebral computed tomography [CCT], NIHSS greater than 11)
  • 2. Within 36 hours after stroke onset
  • 3. Older than 18 years
  • 4. No infection
  • 5. No intracerebral bleeding

排除标准

  • 1. Immunosupressive therapy
  • 2. Pregnancy
  • 3. Antibacterial therapy within the last 24 hours before inclusion
  • 4. Contraindication for moxifloxacin

研究者

发起方
Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)

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