CTRI/2014/09/005002招募中未知
nderstanding the genetic basis of chemotherapy resistance in gingivobuccal squamous cell carcinoma (GSCC)
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- DBT
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
入选标准
- •1.Previously untreated borderline resectable GB SCC i.e T4a lesions
- •2.Histological proven diagnosis of squamous cell cancer
- •3.Signed informed consent
- •4.Adequate organ function
- •Hematological- Hb > 9 g/dL, ANC >= 1.5 x 109/L, platelets >= 100 x 109/L.
- •Liver functions- bilirubin<= 2x upper limit normal (ULN), S. albumin>=30 g/L.
- •Renal function- Creatinine <= 2 ULN, Creatinine clearance > 30 mL/min.
- •Performance score (KPS) > 80 or ECOG <= 2
排除标准
- •1.Distant metastasis present
- •2.Serious co-morbidities such as severe cardiac failure or severe pulmonary compromise or severe and active infections.
- •3.Patients not suitable for any chemotherapy.
- •4.Patient is currently enrolled in a clinical trial for another investigational therapy.
- •5.Pregnancy
- •6.Patients in whom chemotherapy is advised for a palliative intent will not be considered for the study because chemotherapy will be very varied and may be metronomic in nature which will cause wide differences in the final analysis
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