NCT02067650已完成不适用
Ultrasound Findings of Finger, Wrist and Knee Joints in Mucopolysaccharidosis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- Power Doppler
研究概览
简要总结
Hardly any imaging studies specifically addressing the articular and periarticular structures in MPS patients are available at this point. The investigators propose to do for the first time a pilot study using musculoskeletal ultrasound in patients with various types of MPS.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 2 Years 至 99 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Power Doppler
时间窗: one time exam
The primary objective is to determine whether patients with various types of MPS and at various stages of the disease exhibit abnormalities of the finger, wrist and knee joints as assessed by grey scale and Power Doppler ultrasonography.
次要结局
- Ultrasound scanning technique(one time scan)
- Findings of synovitis or tenosynovitis(one time scan)
- Differences between MPS I and IV(one time scan)
- Differences between ERT and BMT(one time scan)
- Differences between severe and attenuated phenotypes(one time scan)
研究者
Johannes Roth
Principal Investigator
Children's Hospital of Eastern Ontario
研究点 (1)
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