External Oblique and Rectus Abdominis Plane (EXORA) Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Time to the 1st rescue analgesia
研究概览
简要总结
This study aims to compare the effects of the external oblique and rectus abdominis plane (EXORA) block and the quadratus lumborum block (QLB) on postoperative analgesia in patients undergoing laparoscopic cholecystectomy (LC).
详细描述
Laparoscopic cholecystectomy (LC) is a proven, gold standard surgical procedure for the management of gallbladder stones.
The quadratus lumborum block (QLB) is a regional block that would appear to be similar to the posterior TAP block, although the drug injection area is deeper and more dorsal than the transverse abdominal aponeurosis.
The external oblique and rectus abdominis plane (EXORA) block is an emerging technique providing a sensory block to the anterolateral abdominal wall.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 18 to 65 years.
- •Both sexes.
- •American Society of Anesthesiology (ASA) physical status I-II.
- •Undergoing laparoscopic cholecystectomy (LC) under general anesthesia.
排除标准
- •History of allergies to local anesthetics.
- •Opioid dependency.
- •Bleeding or coagulation disorders.
- •Psychiatric and neurological disorder.
- •Local infection at the site of injection.
- •Body mass index (BMI) >
- •Hypertension.
- •Uncontrolled diabetes mellitus.
研究组 & 干预措施
QLB group
Patients will receive a quadratus lumborum block (QLB) using 20ml of bupivacaine 0.25%.
干预措施: Quadratus lumborum block (Other)
EXORA group
Patients will receive an external oblique and rectus abdominis plane (EXORA) block using 20ml of bupivacaine 0.25%.
干预措施: External oblique and rectus abdominis plane block (Other)
结局指标
主要结局
Time to the 1st rescue analgesia
时间窗: 24 hours postoperatively
Time to the first request for the rescue analgesia (time from the end of surgery to first dose of morphine administrated).
次要结局
- Total morphine consumption(24 hours postoperatively)
- Intraoperative fentanyl consumption(Intraoperatively)
- Degree of pain(24 hours postoperatively)
- Incidence of adverse events(24 hours postoperatively)
研究者
Mohammed Said ElSharkawy
Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University