A comparative study on the efficacy of oral Pregabalin versus intravenous Dexmedetomidine as premedication on hemodynamic response during laryngoscopy in elective surgeries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Mean arterial pressure, Blood pressure, Heart rate
研究概览
简要总结
This study is a randomized , double blind, parallel group , single centered trial comparing efficacy of Oral Pregabalin and intravenous Dexmedetomidine as premedication in 100 patients undergoing general anesthesia for elective surgeries that will be conducted in Sri Venkateshwaraa medical college hospital and research centre . The primary outcome measures will be change in Mean arterial pressure, Blood pressure, Heart rate during laryngoscopy and intubation . The secondary outcomes will be incidence of any side effects intraoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Age groups between 18 and 65 years, Â
- •American Society of Anesthesiologists physical status Class I or II
- •Elective surgeries requiring general anesthesiaÂ.
排除标准
- •1.Patients with medical disorders like cardiovascular, renal and liver diseases 2.Patients with anticipated difficult airway  3.Patients who are already taking pregabalin or other anticonvulsants and sedatives, beta blockers . 4.Patients who are not willing to participateÂ.
结局指标
主要结局
Mean arterial pressure, Blood pressure, Heart rate
时间窗: Baseline,30 mins after oral drug , during intubation,1 min,3 min , 5 min, 10 min , every 15 min after that till 4 hours
次要结局
- any adverse effects of the drug(throughout surgery)
