跳至主要内容
临床试验/CTRI/2024/03/064189
CTRI/2024/03/064189尚未招募不适用

A comparative study on the efficacy of oral Pregabalin versus intravenous Dexmedetomidine as premedication on hemodynamic response during laryngoscopy in elective surgeries

Dr Radhakrishnan A professor1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年1月4日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
Mean arterial pressure, Blood pressure, Heart rate

研究概览

简要总结

This study is a randomized , double blind, parallel group , single centered trial comparing efficacy of Oral Pregabalin and intravenous Dexmedetomidine as premedication in 100 patients undergoing general anesthesia for elective surgeries that will be conducted in Sri Venkateshwaraa medical college hospital and research centre . The primary outcome measures will be change in  Mean arterial pressure, Blood pressure, Heart rate during laryngoscopy and intubation . The secondary outcomes will be incidence of any side effects intraoperatively.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Age groups between 18 and 65 years, Â
  • American Society of Anesthesiologists physical status Class I or II
  • Elective surgeries requiring general anesthesiaÂ.

排除标准

  • 1.Patients with medical disorders like cardiovascular, renal and liver diseases 2.Patients with anticipated difficult airway  3.Patients who are already taking pregabalin or other anticonvulsants and sedatives, beta blockers . 4.Patients who are not willing to participateÂ.

结局指标

主要结局

Mean arterial pressure, Blood pressure, Heart rate

时间窗: Baseline,30 mins after oral drug , during intubation,1 min,3 min , 5 min, 10 min , every 15 min after that till 4 hours

次要结局

  • any adverse effects of the drug(throughout surgery)

研究者

发起方
Dr Radhakrishnan A professor
申办方类型
Private medical college

研究点 (1)

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