NCT04782674Unknown不适用
A Prospective Study on the Application of Saliva EBV-DNA Detection in EBV Infection Related Diseases
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Monitoring
研究概览
简要总结
This study is a single-center, prospective, observational clinical study to evaluate the Application of saliva EBV-DNA Detection in EBV Infection Related Diseases
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 3 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •According to the HLH-04 diagnostic criteria, it meets the HLH diagnostic criteria. EBV infection occurs in cells with EBV-DNA copy number significantly increased in peripheral blood or tissue, or where EBV coding small RNA(EBER) is detected in tissue or peripheral blood. Or Straus' 1988 diagnostic criteria for CAEBV.
- •Informed consent
排除标准
- •Patients who cannot cooperate with saliva collection
- •Patients who are unwilling to cooperate with the project research according to the project research plan.
结局指标
主要结局
Monitoring
时间窗: 2 to 12 weeks after treatment
The sensitivity and specificity of saliva EBV-DNA detection level as a monitoring method for EBV infection-related diseases, and whether it can replace peripheral blood EBV-DNA monitoring
Diagnosis
时间窗: baseline
The sensitivity and specificity of saliva EBV-DNA detection level as a diagnosis for EBV infection-related diseases, and whether it can replace peripheral blood EBV-DNA monitoring
次要结局
未报告次要终点
研究者
Zhao Wang
Principal Investigator
Beijing Friendship Hospital
研究点 (1)
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