临床试验/CTRI/2025/01/079170

CTRI/2025/01/079170已完成不适用

A randomised comparative study of pre-op nebulization with Fentanyl, Dexmedetomidine or Magnesium Sulphate for blunting haemodynamic response to Laryngoscopy and Tracheal intubation

Dr Subashini KJ1 个研究点分布在 1 个国家目标入组 171 人开始时间: 2025年2月10日最近更新: 2025年10月6日

试验速览

阶段: 不适用
状态: 已完成
发起方
入组人数: 171
试验地点: 1
主要终点: To compare the efficacy of nebulized drugs.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

THIS STUDY IS RANDOMIZED COMPARATIVE STUDY OF PRE-OP NEBULIZATION WITH FENTANYL, DEXMEDETOMIDINE OR MAGNESIUM SULPHATE FOR BLUNTING HAEMODYNAMIC RESPONSE AND TRACHEAL INTUBATION. THE PRIMARY OBJECTIVE IS TO COMPARE THE EFFICACY OF NEBULIZED DRUGS AND SECONDARY OBJECTIVE IS TO ASSESS THE ONSET AND DURATION OF ATTENUATION RESPONSE AND TO REPORT ANY ADVERSE REACTIONS.

研究设计

研究类型: Interventional
分配方式: Coin toss, Lottery, toss of dice, shuffling cards etc
盲法: Participant Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Patients who are willing to participate in the study and giving valid consent
•Patients with asa grade 1 and 2 in routine cases
•Patients with mpc grade 1 and 2
•Elective surgeries.

排除标准

•1.Patients who have uncontrolled diabetis mellitus or uncontrolled hypertension 2.Patients with coagulopathies or on anticoagulation medications 3.Patients who is having known hypersensitivity to study drugs 4.Patients with mpc 3 and 4, video laryngoscope guided or awake fiberoptic guided intubation.

结局指标

主要结局

To compare the efficacy of nebulized drugs.

时间窗: Baseline, after 1 min , 2 min , 3 min , 5 min , 10 min , 15 min , 20 min, 25 min, 30 min, 1 hour, 2 hours.

次要结局

1. To assess the onset of(attenuation response caused)

研究者

发起方

Dr Subashini KJ

申办方类型

Other [self]

责任方

Principal Investigator

主要研究者

Dr Subashini KJ

Grant Goverment Medical College and Sir JJ Hospital.

研究点 (1)

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