Evaluation of Dry Eye Following Transepithelial Photorefractive Keratectomy in Comparison to Conventional LASIK: a Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- qualitative assessment of dry eye syndrome
研究概览
简要总结
The aim of the study is to evaluate the severity of dry eye syndrome following excimer laser vision correction using no-touch all-laser photorefractive keratectomy in comparison to conventional lasik
详细描述
Prospective interventional clinical study 2 groups: Group A : 20 eyes of 10 patients undergoing transepithelial PRK Group B: 20 eyes of 10 patients undergoing LASIK using mechanical microkeratome Tear Break Up Time and Schirmer 2 tests are used to evaluate severity of dry eye before surgery and 1 , 3 and 6 months postoperative Follow up period : 6 months
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Myopia -1 to -6 diopters
- •Astigmatism -0.5 to - 4 diopters
排除标准
- •Pregnancy and lactation
- •Keratoconus
- •Previous refractive surgery
- •Previous herpetic keratitis
研究组 & 干预措施
Transepithelial PRK
20 eyes to undergo a no touch , all-laser advanced surface ablation technique termed transepithelial PRK using the Amaris laser platform (Schwind eye-tech solutions Gmbh, Germany)
干预措施: transepithelial PRK (Procedure)
Conventional LASIK
20 eyes to undergo LASIK using a mechanical microkeratome (M2, Moria Surgical, Antony, France) and the Mel 80 excimer laser system(Carl Zeiss Meditec)
干预措施: LASIK (Procedure)
结局指标
主要结局
qualitative assessment of dry eye syndrome
时间窗: 6 months
Tear Break Up time is used as a qualitative measure of dry eye after surgery
quantitative of dry eye after surgery
时间窗: 6 months
Schirmer test is used as a quantitative measure of dry eye after surgery
次要结局
- haze(6 months)
研究者
Ahmed Mohamed Sherif
Dr Ahmed Sherif
AL-Nour Eye Hospital