CLINICAL STUDY OF VIDANGADI PINDI AND KHADIRASHTAKA KWATH SIDDHA TAILAM IN THE MANAGEMENT OF EKKUSHTHA W.S.R.TO PSORIASIS
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- reduce the symptoms of psoriasis
研究概览
简要总结
Ayurved is an ancient medical science. It is not only medical system but also it includes life philosophy in which there is description of seasonal regimen such as Dincharya, Ratricharya and Ritucharya. A person who follows this seasonal regimen described in Ayurved Samhita’s is always healthy. Intake of Mithya Ahara Vihara causes suffering from various diseases. In Ayurved classics, there is complete description of how to regain health. Two main aims of Ayurved are to protect health of healthy person and to cure disease of diseased person (ch. su. 30/26).
Person is said to be healthy when Dosha, Dhatu (digestive fire), Dhatvagni is in proper state and Mana (mind), Atma (soul),
Indriya (motor and sensory organs) are in pleasant state (su. Su. 15/48). Definition given by Acharya Sushrut is accepted by W.H.O. (world health organization).
According to W.H.O. Health is a complete state of physical, mental, social and spiritual wellbeing not merely the absence of disease.
Now a day, disease related to skin is very common problem. According to Roxburgh book of common skin disease, about 10-15% of persons are suffering from dermatitis. Due to any type of skin deformity, person has to face physical, mental and social problems. Under dermatological disorders, Ek-kushtha (psoriasis) is commonly caused chronic skin disorder due to unknown reasons.
It is found in about 2% of people of the world. In Psoriasis, there is inflammation and disease spread at the rate of 10 times greater than that of normal skin. It affects people of all genders and castes. In this, there are Pidika (pimples) and Chakkate (Rashes) in the skin, which are clearly different from normal skin. Mostly it is found in head, upper back, lumbar region, arms, legs, especially in the outer surface of elbows and knees.
In Ayurved, all Twaka (dermatological) related disorders included under Kushtha. Due to various reasons, the natural color of the skin gets distorted due to leprosy. In case if proper treatment is not provided then entire body of the patient gets affected.
Skin also has special significance like other organs. It is the natural protective shield of the body which prevents various pathogenic causes like bacteria, viruses etc from entering the body. The first visible organ is skin and it covers whole extremities of the body.
BASIS OF TOPIC SELECTION
In the present era, dermal disorder is a serious problem. This disease affects a person not only physically but mentally as well. In terms of beauty skin is very important, but psoriasis is a skin disorder whose effects are seen in a person confidence and social activities.
Psoriasis is one of the most common dermatologic diseases, affecting up to 1-2% of the world’s population. It occurs in all age groups and about equally in men and women. The main cause for the origin of disease is irregular eating habits, heavy diet etc.
BASIS OF MEDICINE SELECTION
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In Ayurveda, various formulations are described for the treatment of leprosy in which Sushrutokta Aragvadhadigana has been selected for the treatment of Psoriasis.
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Most of the constituent substances of this medicinal formulation having Bitter, astringent taste, Ushna Virya and Katu Vipaka which helps on balancing Kapha Dosha. Balancing Vata Dosha by having properties like Ushna Virya and Katu Vipaka. Therefore this medicinal formulation will be beneficial in the treatment of Psoriasis.
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In modern medical science, Psoriasis has been called as incurable.
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Steroid and immunosuppressive drugs are used for its treatment from which patient gets immediate benefit but after sometime the disease arises again. Using of these drugs doesn’t completely reduce the disease.
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All components of the selected drug substance are easily accessible.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •based on clinical symptoms mentioned in classical text book of ayurveda and modern.
排除标准
- •below 18 year and more than 60 year patient with other systemic disorder like chronic cardiac illness tuberculosis, cancer, AIDS and other endocrine disorder.
结局指标
主要结局
reduce the symptoms of psoriasis
时间窗: 90 days
次要结局
- improve the Quality of Life(90 days)
