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临床试验/NCT04553653
NCT04553653已完成不适用

Improving Acute Hypertension Management Through Emergency Department Checklist

Johns Hopkins University2 个研究点 分布在 1 个国家目标入组 1,161 人开始时间: 2019年6月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,161
试验地点
2
主要终点
Change in frequency of diagnosis of hypertensive emergency

研究概览

简要总结

The investigators hypothesize that the implementation of a checklist in acute severe hypertension would result in improving short and long-term outcomes of patients with acute severe hypertension treated in the emergency department (ED). The investigators hypothesize that in the short-term, a checklist would improve the diagnosis and management of end-organ damage as well as reduce the length of stay of acute severe hypertensive patients in the ED. The investigators hypothesize that the checklist will result in better compliance with anti-hypertensive medications than without the checklist at six-month post-discharge.

详细描述

Hypertension is a global public health issue and results in over 10 million deaths every year. The disease affects one-third of people living in low- and middle-income countries (LMICs) and contributes to half of all productivity losses in LMICs due to non-communicable diseases. Though hypertension often presents as a chronic asymptomatic illness, hypertension-related emergencies represent a significant burden to the health care system. Acute severe hypertension [i.e., systolic blood pressure (SBP) ≥ 180 mmHg or diastolic blood pressure (DBP) ≥ 110 mmHg] make up to 5% of all emergency admission. One-third of these patients present with end-organ damage; a condition called a hypertensive crisis. More worrisome is the fact that a number of ED visits, as a result, severe acute hypertension and hypertensive crises have almost tripled between 2006 and 2013 in the US. Treatment approaches to managing acute severe hypertension (~5% of ED patients) are largely unclear and only 6% of ED patients with acute severe hypertension receive appropriate work-up for the end-organ damage, indicating a huge care gap. One approach, which has been used successfully in managing other complex and critical conditions, is the use of checklists. Checklists are a listing of actions to be performed in a given clinical setting with the aim of improving adherence to standards, reducing errors and thus improving patient outcomes. The investigators hypothesize that the use of a Checklist, if appropriately implemented, can lead to an improvement in the care of patients presenting with hypertensive crisis. During this study, the investigators will measure the prevalence of acute severe hypertension and assess the current quality of care for these patients. This will be followed by the development of a checklist for the management of the hypertensive crises in the ED. The investigators will follow these patients to see the impact of the checklist on the quality of care and long-term outcomes.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Sequential
主要目的
Treatment
盲法
Single (Participant)

盲法说明

Participants will be masked. Investigators and care providers are not masked due to the obvious design and logistics challenges.

入排标准

年龄范围
25 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults who visit the Aga Khan University Hospital Emergency Department with acute severe hypertension
  • able to provide consent to participate
  • Age >25 years of age
  • Meeting the criteria of acute severe hypertension (SBP>180 and DBP>110).

排除标准

  • Patients not providing consent or are unconscious are excluded from participation.

结局指标

主要结局

Change in frequency of diagnosis of hypertensive emergency

时间窗: Baseline and 6 months after checklist implementation

The frequency of correct diagnosis of hypertensive emergency in patients with severe hypertension with evidence of end-organ damage in the ED before and after the implementation of the checklist.

次要结局

  • Change in the use of appropriate medications for treatment of hypertensive emergency(Baseline and 6 months after checklist implementation)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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