NL-OMON52822招募中2 期
PANcreatic Cancer lOcalized disease in frail or elderly patients unfit for both chemotherapy and surgery treated with Stereotactic Ablative Radiotherapy (PANCOSAR): a multicenter randomized controlled trial - PANCOSAR
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 98
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Pathology proven localised (non-metastasized) PC
- •Patients unfit for both surgery and systemic chemotherapy (i.e. KPS 50-70;
- •WHO 2 or favourable WHO3) or patients who refuse surgery or chemotherapy.
- •In case of prior treatment with chemotherapy: A maximum of two cycles of
- •chemotherapy is aloud for inclusion. The interval between the last cycle of
- •chemotherapy and the first fraction of radiation therapy should be at least six
- •weeks. Additionally, in the case patient suffered from side effects of the
- •chemotherapy these have to score equal or below 1 (CTCAE v.5.0) in before the
- •first fraction of radiation therapy is delivered.
- •Written informed consent
排除标准
- •Age <18 years
- •Administration of more than two cycles of chemotherapy
- •Distant metastasis
- •Imminent bowel obstruction
- •Active bleeding
- •Uncontrolled infection
- •Contra-indications for MRI (only for VUmc and UMCU)
- •- pacemakers or implanted defibrillators, deep brain stimulators, cochlear
- •implants. Patients who have a metallic foreign body in their eye, or who have
- •an aneurysm clip in their brain, cannot have an MRI scan since the magnetic
- •field may dislodge the metal
- •- Patients with severe claustrophobia not able to tolerate an MRI scan
- •- Patients with a non-MR-compatible (hip/knee/jaw) prosthesis
研究者
相似试验
Unknown
不适用
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尚未招募
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终止
1 期
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招募中
不适用
Pancreatic Locally advanced Irresectable Cancer AblatioN (PELICAN trial)Locally advanced pancreatic cancernon-resectabel pancreatic tumor10017998NL-OMON56404Amsterdam UMC174
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不适用
Individuals at high-risk for developing pancreatic cancer: surveillance by endosonography and magnetic resonance imaging: FAMILIAL PANCREATIC CANCER SURVEILLANCE STUDYpancreatic neoplasia1008362410017991pancreatic cancerNL-OMON31426Erasmus MC, Universitair Medisch Centrum Rotterdam150