Inherited Thrombophilia and Thrombotic Risks in Inflammatory Bowel Disease During Activity and Remission
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 93
- 主要终点
- Comparison between the number of IBD patients with tendency to thrombosis in cases of activity-
研究概览
简要总结
Inherited thombopllia and thrombotic risks in inflammatory bowel Disease during activity and remission
详细描述
Inflammatory bowel diseases (IBD) are systemic conditions characterized by multiple intestinal and extra-intestinal manifestations related to the associated chronic inflammatory state. Among their diverse extra-intestinal complications, venous thromboembolism (VTE) remains one of the most under recognized causes of morbidity and mortality in these patients, highlighting the need for a better understanding of the underlying mechanism of hypercoagulability, in addition to the role of acquired and inherited risk factors that further increase the risk of thrombosis with its impact on patients' outcomes.[1, 2]
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age (18yrs - 65yrs) both sex
排除标准
- •Presence of acquired cause (pregnancy, recent surgery, history of drug, History of malignant Disease, History of blood or blood product transfusion in last 4 weeks)
结局指标
主要结局
Comparison between the number of IBD patients with tendency to thrombosis in cases of activity-
时间窗: Baseline
-investigate the presence of multiple mutations associated with IBD patients with or without vascular complications.
次要结局
未报告次要终点
研究者
Asmaa mohammed abdelaal abdelaal
Dr Asmaa Abdelaal
Assiut University