临床试验/NCT01014728

NCT01014728已完成不适用

Comparison of Intraoperative Bleeding During Endoscopic Sinus Surgery Between Patients Receiving Total Intravenous Anesthesia With Propofol and Patients Receiving an Inhalational Anesthetic With Sevoflurane

University of Chicago1 个研究点分布在 1 个国家目标入组 33 人开始时间: 2009年11月最近更新: 2014年2月14日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Chicago
入组人数: 33
试验地点: 1
主要终点: Estimated Blood Loss

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to compare the blood loss during sinus surgery looking at two different types of anesthesia: either intravenous anesthesia with propofol or inhalational anesthesia with sevoflurane.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: 18 Years 至 85 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•male or female patients who are 18 years of age or older,
•ASA grade 1 (normal otherwise healthy patient),
•ASA grade 2 (patient with mild systemic disease),
•patients who have chronic sinusitis with or without nasal polyps.

排除标准

•pregnancy,
•abnormal coagulation panel
•preoperative use of NSAIDS or ASA medications within 7 days,
•end-stage renal disease,
•allergy to any of the used medications,
•maximal body mass index over 35

研究组 & 干预措施

Intravenous anesthesia

Active Comparator

Intravenous anesthesia with propofol for endoscopic sinus surgery

干预措施: propofol (Drug)

Inhalation anesthesia

Active Comparator

Inhalation anesthesia with sevoflurane for endoscopic sinus surgery

干预措施: sevoflurane (Drug)

结局指标

主要结局

Estimated Blood Loss

时间窗: from the start of surgery to the end of surgery, up to 6 hours

Estimated blood loss in milliliters per hour is calculated by subtracting the volume of total irrigation used during the case from the total amount of fluid in the suction canister at the end of surgery and dividing by surgical time in hours.

次要结局

Anesthesiologist Numeric Rating Scale (ANRS)(at the end of surgery (up to 6 hours))
Surgeon's Numeric Rating Scale (SNRS)(at the end of surgery (up to 6 hours))

研究者

发起方

University of Chicago

申办方类型

Other

责任方

Sponsor

研究点 (1)

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