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临床试验/NCT05529537
NCT05529537已完成不适用

The Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis Patients

Selcuk University2 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2022年8月17日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
39
试验地点
2
主要终点
Rheumatoid Arthritis Quality of Life Scale (QOL-RA)

研究概览

简要总结

Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage occurs in cartilage, bone and joints. This damage leads to severe functional limitations and deterioration in quality of life. Synovial tissues are the main site of involvement. Manual lymph drainage reduces the levels of inflammatory mediators associated with edema and pain in the acute phase. On the basis of this concept; Stimulating the lymph system and increasing circulation, removing biochemical residues, regulating sympathetic and parasympathetic system responses, and thus reducing edema and pain. The increase in cardiac parasympathetic activity measured after MLD also contributes to relaxation. In addition to the transport of lymphatic fluid, manual lymph drainage stimulates free nerve endings in the skin with the touches it contains. Gentle stimulation to the skin increases tactile input and closes the pain pathways. In addition, the superficial relaxation and warming provided by soft stimulation creates an effect on the autonomic nervous system and activates the parasympathetic system. The aim of this study is to evaluate the effect of manual lymphatic drainage on upper extremity functionality in individuals with rheumatoid arthritis.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
25 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Diagnosed with RA according to ACR criteria
  • Being between the ages of 18-65
  • Volunteering to participate in the study

排除标准

  • Presence of neuromuscular disease
  • Having difficulty walking
  • Cognitive impairment
  • Having systemic disease such as diabetes mellitus and osteoarthritis
  • History of upper extremity sIf you have Hand Deformity

结局指标

主要结局

Rheumatoid Arthritis Quality of Life Scale (QOL-RA)

时间窗: 10 minutes

In the scale consisting of 30 questions; questions are scored as "yes-1" and "no-0". The scores obtained range from 0-30, and high scores indicate poor quality of life.

pressure pain threshold

时间窗: 5 minutes

It is used for the assessment of sensitivity to pain and the determination of pressure perception. will be evaluated with a digital algometer device with a surface area of 1 cm2 and a sensitivity of 0.25 kg/cm2 (Jtech Medical Industries, ZEVEX Company, USA).

hand grip strength

时间窗: 5 minutes

The Jamar hand dynamometer, which is recommended by the American Association of Hand Therapists (AETD) and has high validity and reliability in many studies and is therefore accepted as the gold standard, will be used.

finger grip strength

时间窗: 5 minutes

Finger pinchmeter (Baseline) will be used to measure finger grip strength.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Emine Cihan

principal investigator

Selcuk University

研究点 (2)

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