Cognitive Behavioral Therapy for Adolescents With Excessive Worry - a Case Series
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Penn State Worry Questionnaire for Children (PSWQ-C)
研究概览
简要总结
This case series aims to test the feasibility and acceptability of streamlined cognitive behavioral therapy (CBT) for adolescents with excessive worry. The treatment protocol focuses on reducing intolerance of uncertainty and the hypothesis is that this will help reduce worry.
详细描述
This pilot study aims to test a new form of Cognitive Behavioral Therapy for adolescents with excessive worry. The investigators will include 12 participants with excessive worry and test the treatment which focuses on reducing intolerance of uncertainty (IU) in order to reduce worry.
Participants will be randomized to either one, two or three weeks of weekly baseline measurements prior to starting treatment, and will thus work as their on controls in this case series design.
Primary outcome measures will be collected at 12 weeks after treatment start. Participants will be followed up at three months after treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 13 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A score on PSWQ-C of at least 22
- •Age between 13 and 17 years
- •Ability to read and write in Swedish
- •A parent or caregiver that is able to co-participate in the treatment
- •Participants on psychotropic medication must have been on a stable dose for the last 6 weeks prior to baseline assessment
排除标准
- •Diagnosis of autism spectrum disorder, psychosis, bipolar disorder or severe eating disorder
- •Present risk of suicide
- •Ongoing substance dependence
- •Occurrence of domestic violence
- •Completed CBT for any anxiety disorder within the last 6 months (defined as at least 5 sessions of CBT including in vivo exposure sessions)
研究组 & 干预措施
Cognitive Behavioral Therapy
All participants will receive cognitive behavioral therapy for excessive worry. Focus in treatment will be on reducing participants' intolerance uncertainty through in vivo and imaginary exposure to uncertainty inducing situations and thoughts. Treatment will also contain psycho education about anxiety and worry, as well as planning for maintenance of treatment gains. Parents of the participants will receive support and education about worry through an internet-delivered program.
干预措施: Cognitive behavioral therapy (Behavioral)
结局指标
主要结局
Penn State Worry Questionnaire for Children (PSWQ-C)
时间窗: At 12 weeks after treatment starts
Child and parent version
次要结局
- Clinical Global Impression - Severity (CGI-S)(Baseline, 12 weeks after start of treatment and three month after treatment has ended.)
- Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)(Baseline, 12 weeks after start of treatment and three month after treatment has ended.)
- Brief Why Worry-II (Brief WW2)(Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended)
- Revised Children´s Anxiety and Depression Scale (RCADS-C)(Baseline, 12 weeks after start of treatment and three month after treatment has ended.)
- Brief Intolerance of Uncertainty Scale (Brief IUS)(Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended)
- Negative Problem Orientation Questionnaire (NPOQ)(Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended)
- Education, Work and Social Adjustment Scale (EWSAS)(Baseline, 12 weeks after start of treatment and three month after treatment has ended.)
- Clinical Global Impression - Improvement (CGI-I)(At 12 weeks after start of treatment and three month after treatment has ended.)
- Children's Global Assessment Scale (CGAS)(Baseline, 12 weeks after start of treatment and three month after treatment has ended.)
- Brief Cognitive Avoidance Questionnaire (Brief CAQ)(Baseline, weekly during treatment, 12 weeks after treatment starts, and three months after treatment has ended)
研究者
Eva Serlachius
Associate professor
Karolinska Institutet