JPRN-UMIN000011552已完成2 期
Phase II study of XELOX plus bevacizumab as second-line chemotherapy prior oral fluoropyrimidine, irinotecan plus bevacizmab for metastatic colorectal cancer - CCOG 1203
Chubu Clinical Oncology Group (CCOG)0 个研究点目标入组 25 人开始时间: 2013年8月22日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 25
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1)Uncontrolled infection. 2)Patient with symptomatic cardiovascular disease or asymptomatic disease but have been treated 3)Previous history of thoromboembolitic disease,or necessity for antithrombotic drug. 4)Severe lung disease.(Interstitial lung disease or pulmonary fibrosis.) 5)Severe liver disease. 6)Severe renal failure. 7)Previous history of severe drug-induced allergy 8)Intestinal bleeding, ileus, bowel obstruction or uncontrolled peptic ulcer. 9)History of gastrointestinal perforation within 1 year. 10)Uncontrolled severe complications(DM, hypertension, diarrhea, et al.) 11)History of active double cancer. 12)Massive pleural effusion or ascites that required drainage. 13)Brain metastasis 14)Patients with psycho-neurological disease,central nervous system damage,cerebrovascular disorder 15)Patient receiving surgical procedure or such as skin-open biopsy, trauma surgery, or other more intensive surgeries within 4 weeks or aspiration biopsy within a week. 16)Patient with untreated traumatic bone fracture. 17)Diathesis of bleeding (history of hemoptysis,including cavitation and/or necrosis in lung metastasis confirmed by imaging),coagulopathy. 18) Systemic administration of antiplatelet drug 19)Administration of immunosuppressants associated with organ transplantation 20)Patient who have peripheral nerve disorder 21)Pregnant women, possibly pregnant women, wishing to become pregnant, and nursing mothers. 22)Previous history of severe side effects for fluoropyrimidine 23)Not appropriate for the study at the physician's assessment
研究者
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