NCT02909192进行中（未招募）不适用
Bright Light Modulation of Non-motor Symptoms in Parkinson's Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 65
- 试验地点
- 2
- 主要终点
- Parkinson's Disease Sleep Scale (PDSS-2) score to measure sleep quality
研究概览
简要总结
Disruption of sleep and alertness is one of the most disabling non-motor symptoms of Parkinson's disease (PD). Mechanisms leading to impaired sleep and alertness in PD are not well understood, and treatment options remain limited. The proposed research will examine markers of the circadian system, sleepiness and sleep quality in PD patients. Further, the project will examine effects of bright light exposure on circadin function, sleep and alertness in PD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Parkinson's Disease Sleep Scale (PDSS-2) score to measure sleep quality
时间窗: 8 weeks
次要结局
- Epworth Sleepiness Scale (ESS) score to measure daytime sleepiness(8 weeks)
- Plasma melatonin levels collected through blood samples to measure melatonin amplitude and circadian regulation(8 weeks)
- Non-Motor Symptoms Assessment Scale for Parkinson's Disease (NMSS) score to measure the severity and frequency of non-motor symptoms(8 weeks)
研究者
Aleksandar Videnovic, MD
Assistant Neurologist
Massachusetts General Hospital
研究点 (2)
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