Single arm clinical study To evaluate the efficacy of Ashwagandha churna in Dhatukshayajanya Sandhigatavata with special reference to serum calcium

Sandhigatavata

Acharyas of Ayurveda (Charaka , Sushrut and Vagbhata ) have included Vatavyadhi in Astamahagada .There are several Vatavyadhi out of which Sandhigatvata is one of the most common .Acharyas explained this vyadhias Sandhigatanile with clinical signs and symptoms of Shotha(oedema),Vatapurnadritisparsha (on palpation revealed as air filled bags ) and pain with Prasarana andAkunchana ( movement ).In old age, all Dhatus undergo Kshaya (degeneration), thus this leadsto Vataprakopa and making individual prone to many diseases. Among them Sandhigatvata(Osteoarthritis)is on top most position.

Sandhigatvata may occur in any joint of the body. Etiological factors has been explained by Charaka Acharya for vitiation of Vata including diet habit,depletion of Dhatu and path obstruction of Vata Vitated vata is them ainfactorin Sandhigatvata.

The description of Sandhigatvata in classical Ayurvedic texts closely resembles to the condition of Osteoarthritis in modern science. Osteoarthritis is an abnormality of synovial joints characterized by softening, splitting and fragmentation (fibrillation) of auricular cartilage not attributed to direct contact within inflammatory tissue

Serum Calcium is a blood test to measure the amount of calcium in the blood. Serum calcium is measured to monitor bone disease or calcium regulation disorder .That’s why the test can be applicable in Dhatukshayaja Sandhigatvata that is osteoarthritis.

Ashwagandha churna retain calcium and phosphorus in body. Ashwagandha is vatahara so it is useful in vata vyadhi.