Physical Functional Impacts of Rehabilitation in Patients With Human Lymphotropic Virus Type I
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Respiratory muscular strenght
研究概览
简要总结
In our times, it is known that approximately 5% of patients seropositive for HTLV-1 may desengage a frame with several neurological disorders, which is called myelopathy associated with HTLV-1, characterized for gait, decreased dynamic balance and limitation of walking independence the use of walkers, crutches as in wheelchairs. This evolution of the disease is based, above all, on muscle changes, such as inflammation of the muscles, which contributes to the attenuation of muscle capacity . In addition, muscle changes caused by HTLV-1 also affect the respiratory muscles, causing a change in respiratory mechanics, which can impair alveolar ventilation and, therefore, the development of a restorative respiratory disorder, reducing total lung capacity. Therefore, it is perceived the importance of offering planned rehabilitation according to the global assessment of the health status of these patients, considering their influence on activities of daily living.The focus of this study is on the weekly respiratory muscle training, as assessed by mensuration maximal inspiratory pressure, showed significant results in improving lung capacity and in this way promoting the prevention of pulmonary complications. Therefore, the protocol proposed by the present study includes respiratory muscular training plus resistance exercise, assessing the impact on both the strength muscular respiratory to as peripheral muscles, through the palmar pressure test and consequent enhancement of quality life and functionality of these patients. Furthermore, it will be possible to contribute to the knowledge of society and the scientific community about this theme, which is still very small in the world literature.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Seropositive carriers for HTLV-1 with PET
排除标准
- •lung diseases
- •heart disease
- •arterial hypertension
- •cognitive impairments
结局指标
主要结局
Respiratory muscular strenght
时间窗: from baseline respiratory muscle stenght to 5 weeks
The assessment of respiratory muscle strength will be carried out weekly by measuring the maximum inspiration pressure
Functional capacity
时间窗: from baseline functional capacity to 5 weeks
The assessment of functional capacity will be carried out weekly by six minute walk test
次要结局
未报告次要终点
研究者
Rodrigo Santiago Barbosa Rocha, Phd
Researcher
Universidade Metodista de Piracicaba
