Effect of Dry Needling on Insulin Resistance in Obese Post- Menopausal Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- HOMA-IR
研究概览
简要总结
The aim of the study is to determine the effect Dry Needling of on insulin resistance in obese postmenopausal women.
详细描述
Insulin resistance and abdominal obesity have a negative impact on quality of life of postmenopausal women. Obesity and, more specifically, the level of intra-abdominal fat, are positively associated with cardiovascular disease and cardiovascular disease risk factors such as increased plasma lipids and lipoproteins, hyperinsulinemia, and insulin resistance. This study has shown associations among menopause, body fat, and body fat distribution, suggesting that increased abdominal fat distribution could partially mediate the increased cardiovascular disease risk of postmenopausal women .
Abdominal obesity can reflect excess of visceral fat tissue or subcutaneous or both. Visceral fat contributes to the pathogenesis of glucose intolerance and insulin resistance. Insulin resistance is an impaired condition of glucose absorption that induced by insulin .It represents a significant medical and socioeconomic issue impacting women's health and quality of life. So there is clinical experience and documentation for the effectiveness of Dry Needling in the treatment of insulin resistance in obese post-menopausal women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 48 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• All participants post-menopausal from at least 3 years.
- •All participants' ages will be ranged from 48-60 years old.
- •All participants BMI will exceed 25-30 kg/m
- •All participants waist hip ratio will be equal or more than 0, 90.
排除标准
- •• Surgical liposuction within the last 12 months.
- •Untreated hypo- or hyperthyroidism.
- •Uncontrolled liver, kidney or cardiovascular disease or diabetes.
- •Implanted pacemaker or metal implant.
- •History of thrombophlebitis, any hematological disease.
- •No past or present neurological and musculoskeletal disorders that will have affected health condition.
- •No smoking and drinking habits.
- •No psychological problems.
研究组 & 干预措施
Dry Needle
26 patients who were treated with Dry Needling (three times /week/4 months), abdominal exercises, and medical standard care for insulin resistance.
干预措施: Dry Needle (Other)
Dry Needle
26 patients who were treated with Dry Needling (three times /week/4 months), abdominal exercises, and medical standard care for insulin resistance.
干预措施: abdominal exercises, and medical standard care for insulin resistance (Other)
abdominal exercises and medical standard care for insulin resistance.
While Group (B), 26 patients treated with abdominal exercises and medical standard care for insulin resistance.
干预措施: abdominal exercises, and medical standard care for insulin resistance (Other)
结局指标
主要结局
HOMA-IR
时间窗: 4 months
Outcome measures, HOMA-IR (Homeostasis Model Assessment) will be used to assess insulin resistance. HOMA-IR is a model of interactions between glucose and insulin dynamics that is then used to predict fasting steady-state glucose and insulin concentrations for a wide range of possible combinations of insulin resistance and β-cell function.
次要结局
- ultrasound(4 months)
- BMI by kg/m2(4 months)
- waist circumferences by tape(4 months)
- The surface under the cumulative ranking curve (SUCRA)(4 months)
研究者
Shymaa Mohammed Abdo Mohammed
principle investigator
Cairo University