Prevalence and risk factors of cognitive impairment in chronic kidney disease patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 350
- 试验地点
- 1
- 主要终点
- Prevalence of cognitive impairment in chronic kidney disease patients using MoCA score
研究概览
简要总结
Cognitive impairment has been reported from early stage chronic kidney disease patients. Prevalence of cognitive impairment in chronic kidney disease patients is 20% to 50% and up to 70 % in older patients on dialysis In everyday practice cognitive impairment in chronic kidney disease patients is still underdiagnosed, underreported and undertreated. This research project aims to address these issues. Patients will be included in the study as per inclusion criteria. MoCA test will be administered for each patient and a score of 26 and above will be considered normal and any score below 26 will be considered as cognitive impairment. Total score of 18-25 will be considered as mild cognitive impairment, 10-17 as moderate cognitive impairment and less than 10 as severe cognitive impairment. Variables included in the study age, gender, marital status, years of schooling schooling, alcohol use ,smoking, presence of comorbidities including hypertension, type 2 diabetes mellitus, hypothyroidism and cardiovascular disease. These variables will be analysed as possible risk factors for development of cognitive impairment
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients who belong to chronic kidney disease stage3- stage 5 non dialysis patients.
排除标准
- •1.Patients less than 18 years of age 2.Patients who are not giving consent to the study 3.Patients who had head injury, neurological disorders, encephalopathy.
- •4.Patients taking psychiatric drugs and other drugs that interfere with cognitive functioning 5.Terminally ill patients.
结局指标
主要结局
Prevalence of cognitive impairment in chronic kidney disease patients using MoCA score
时间窗: Outcome will be assessed only at baseline when the patient is recruited.
次要结局
- Risk factors for cognitive impairment in chronic kidney disease patients(outcome will be assessed only at baseline when the patient is recruited)
研究者
Vishnu Sarath
Kasturba Medical College, Manipal
