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临床试验/NCT06610136
NCT06610136已完成不适用

Effects of Acute and Prolonged Caffeine Intake on Neuromuscular Adaptations to Resistance Training in Young Adults

University of Alcala2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2023年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
48
试验地点
2
主要终点
Mean velocity at different %1RM

研究概览

简要总结

Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effect of this supplement on neuromuscular adaptations to strength training.

Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, little is known about the prolonged effects of this supplement on neuromuscular adaptations to strength training.

Objectives: The present study aims to analyze the effects of acute and chronic caffeine intake on neuromuscular adaptations to strength training, according to sex (men vs. women) and type of exercise (bench press vs. squat), as well as on fatigue resistance during repeated sprints, fatigue perception, mood state, reaction time, diet, and potential side effects.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Double (Participant, Investigator)

盲法说明

Statistician

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Age between ≥ 18 and ≤ 35 years.
  • Body mass index (BMI) < 25 kg/m².
  • Physically active subjects (>150 min/week of moderate exercise).
  • Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from performing physical exercise.
  • Participants capable of performing the tests.

排除标准

  • History of neuromuscular, cardiac, or diseases that could affect liver or muscle metabolism.
  • Use of drugs or other stimulants that interfere with caffeine intake and intestinal absorption during the tests and study.
  • Body mass index (BMI) > 25 kg/m².
  • Having undergone prolonged periods of forced physical inactivity during the 6 months prior to the study.
  • Performing strenuous exercise within 48 hours prior to the tests.
  • Failing to replicate the same food intake on the two experimental days.
  • Consuming caffeine after 6 PM on the day prior to training or testing.

结局指标

主要结局

Mean velocity at different %1RM

时间窗: Through study completion, an average of 12 weeks

Measuring bar mean velocity desplacement during bench press and back squat exercises.

Peak velocity at different %1RM

时间窗: Through study completion, an average of 12 weeks

Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.

Mean power output at different %1RM

时间窗: Through study completion, an average of 12 weeks

Measuring during bench press and back squat exercises.

Peak power output and time to reach peak power output at different %1RM

时间窗: Through study completion, an average of 12 weeks

Measuring during bench press and back squat exercises.

Number of repetitions performed at 65%1RM until task failure

时间窗: Through study completion, an average of 12 weeks

In bench press and back squat exercises

Bar velocity deplacement performed in 1 set at 65%1RM until task failure

时间窗: Through study completion, an average of 12 weeks

In bench press and back squat exercises

Power output generated in 1 set at 65%1RM until task failure

时间窗: Through study completion, an average of 12 weeks

In bench press and back squat exercise

次要结局

  • Physical activity (METs-min/wk)(Through study completion, an average of 12 weeks)
  • Resting Metabolic Rate (RMR)(Through study completion, an average of 12 weeks)
  • Maximal Fat Oxidation Rate (MFO)(Through study completion, an average of 12 weeks)
  • Fat mass(Through study completion, an average of 12 weeks)
  • Fat-free mass(Through study completion, an average of 12 weeks)
  • Dietary (g/kg of macronutrients)(Through study completion, an average of 12 weeks)
  • Mood state(Through study completion, an average of 12 weeks)
  • Adverse effects(Through study completion, an average of 12 weeks)

研究者

发起方
University of Alcala
申办方类型
Other
责任方
Principal Investigator
主要研究者

Alberto Pérez-López

Principal Investigator

University of Alcala

研究点 (2)

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Caffeine and Resistance Training in Young Adults | 临床试验