PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 3,000
- 试验地点
- 27
- 主要终点
- The prevalence of albuminuria
研究概览
简要总结
The association between Cardiovascular Disease (CVD) and Chronic Kidney Disease (CKD) is well established. Traditional risk factors for CVD and CKD are similar, with type 2 diabetes mellitus (T2DM) being the most prevalent risk factor. However, CKD is underdiagnosed and undertreated in patients with CVD. Further understanding of the combination of CKD in CVD patients is important to formulate prevention and treatment strategies for CVD patients and high-risk groups, reduce adverse events in CVD patients, and prevent progression of CKD to End Stage Renal Disease (ESRD).
详细描述
The PLACARD study will include approximately 3,000 patients presenting to the cardiology department with type 2 diabetes and cardiovascular disease. The aim of this study was to assess the prevalence of proteinuria (urinary ACR) in type 2 diabetic patients with different cardiovascular diseases, both inpatient and outpatient in the cardiology departments of secondary and tertiary hospitals in China. Participants will be recruited at 30 clinical centers for a period of six months.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years old;
- •Diagnosed T2DM combined with ≥1 CVD (hypertension, coronary heart disease, atrial fibrillation, heart failure);
- •During the data collection period, they went to the outpatient clinic of the cardiology department of the research center, or received treatment in the cardiology department;
- •Ability to self-sign informed consent (electronic /paper).
排除标准
- •Pregnant or lactating women;
- •Dialysis patients;
- •Other diseases that lead to elevated albuminuria, such as severe infection, confirmed primary glomerular disease, etc.;
- •. Malignant tumors being treated (surgery, chemotherapy, radiotherapy or targeted therapy);
- •Cachexia (CSS score ≥ 5 points);
- •Severe liver disease (Child- Pugh grade C) ;
- •Participated in an interventional clinical trial in the past three months.
结局指标
主要结局
The prevalence of albuminuria
时间窗: On the day of patients enrollment.
To assess the prevalence of albuminuria in patients who are combined with type 2 diabetes mellitus and different cardiovascular diseases in inpatient and outpatient cardiology departments of secondary and tertiary hospitals in China.
次要结局
- Evaluate the management of patients with type 2 diabetes mellitus and cardiovascular disease across different levels of cardiology departments in hospitals.(On the day of patients enrollment.)
- Lthe prevalence of microalbuminuria and macroalbuminuria evels of microalbuminuria and macroalbuminuria(On the day of patients enrollment.)
- The prevalence of microalbuminuria and macroalbuminuria(On the day of patients enrollment.)
- To evaluate the related influence factors of albuminuria and the treatment patterns of CKD patients and non-CKD patients in cardiology departments;(On the day of patients enrollment.)
研究者
Chang sheng Ma
Director of Cardiology
Beijing Anzhen Hospital