Different Protocols for Prevention of Atonic Postpartum Hemorrhage During Cesarean Delivery in High Risk Group
试验速览
- 阶段
- 不适用
- 入组人数
- 448
- 主要终点
- Amount of blood loss
研究概览
简要总结
PPH is one of the most leading causes of maternal mortality,. It means loss of 500 ml blood after vaginal delivery and 1000 ml blood after cesarean delivery. Although it's preventable it represents about 27%of maternal deaths. Atony is the main cause of PPH. 70%of PPH corresponds to uterine atony. Uterotonics like oxytocin, misoprostol, ergometrine, carbetocin and combinations of these drugs can be used but until now there is no agreement on medication that can be the most effective.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 19 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant full term>37 w
- •Maternal age 19- 40 3.physical state 1&2 4.patient willing to enter the study
排除标准
- •1.who refuse to participate in study 2.immunocomprmized and patients who had contraindicated from any of drugs used 3.patients with hypersensitivity to any drug
研究组 & 干预措施
Pregnant women who receive oxytocin
干预措施: Syntocinon, papal, misotac (Drug)
Pregnant Women who receive carbetocin
干预措施: Syntocinon, papal, misotac (Drug)
Pregnant women who receive misoprostol
干预措施: Syntocinon, papal, misotac (Drug)
Pregnant women who receive ergometrine
干预措施: Syntocinon, papal, misotac (Drug)
结局指标
主要结局
Amount of blood loss
时间窗: 1 year
Decrease amount of blood loss
次要结局
- Finding the drug most effective with least adverse effects(1 year)
研究者
Randa Wanees Ahmed
Randa Wanees Ahmed
Assiut University