Cohort of Non-small Cell Lung Cancer With Mutation of the Nord Pas de Calais
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 518
- 试验地点
- 2
- 主要终点
- Correlation between clinical factors and mutation status
研究概览
简要总结
The investigators propose to create a database at the regional level, the principle is to include all patients in whom a mutation was detected from a single platform (Lille). The creation of this regional cohort, smaller than the national cohort of Biomarkers France, will perform a more comprehensive collection of clinical data, and molecular monitoring data of patients included. To increase the completeness of the collection of information, it will not be based on voluntary prescribing clinician but will be largely carried out by CRA dedicated to this activity.
详细描述
This is a prospective and retrospective study of a population of patients with mutated non-small cell lung cancer in the Nord Pas de Calais. Retrospective cohort will involve patients with main molecular abnormalities, identifiable from molecular biology platform CRRC, except EGFR and KRAS treated from September 2011 to February 2013.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged ≥ 18 years old
- •Patient with non-small cell lung cancer
- •Detected in the Nord Pas de Calais
- •Monitored in the Nord Pas de Calais
- •Patient must have signed a non-opposition form to the use of medical data
排除标准
- •- No identified mutation
结局指标
主要结局
Correlation between clinical factors and mutation status
时间窗: at baseline
The clinical factors are age, smoking status, occupational and environmental exposure, personal and family background, TNM stage, performance status
次要结局
- Progression-free survival(3 years)
- Overall survival(3 years)
- Number of patients included in a clinical trial dedicated to a certain type of non-small cell lung cancer with mutation(3 years)
- Number of cases per mutation type(3 years)