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临床试验/CTRI/2024/08/071831
CTRI/2024/08/071831尚未招募不适用

Estimation of Generation of Prothrombotic Phenotype in cases of Retinal Vein Occlusion

IMS BHU1 个研究点 分布在 1 个国家目标入组 55 人开始时间: 2024年8月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
55
试验地点
1
主要终点
Thromboelastography

研究概览

简要总结

The aim of the study is to evaluate altered clotting dynamics in cases of Retinal Vein Occlusion using Thromboelastography, which may be useful tool to elucidate its pathophysiology. Further we also try to establish the consequences of platelet neutrophil interactions resulting in increased thrombotic events.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 80.00 Year(s)(—)
性别
All

入选标准

  • All cases of Retinal Vein Occlusion attending the outpatient department of RIO, IMS, BHU .
  • Cases giving written consent to participate in the study.

排除标准

  • Acute inflammatory state Patients on anti platelet and anti-coagulant drugs Patients with glaucoma or any optic nerve disorder Patients suffering from major systemic diseases like diabetes mellitus, cardiovascular diseases, anemia, cancer Pregnant and lactating women Patients with other ocular disorders.

结局指标

主要结局

Thromboelastography

时间窗: Day 0 to Day 7

Flowcytometry for assessing platelet neutrophil aggregates circulation

时间窗: Day 0 to Day 7

OCT macula

时间窗: Day 0 to Day 7

次要结局

  • 1.Best corrected visual acuity(2.Slit Lamp Biomicroscopy)

研究者

发起方
IMS BHU
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Deepak Mishra

Regional Institute Of Ophthalmology,Institute Of Medical Sciences, Banaras Hindu University

研究点 (1)

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