NCT06889805招募中不适用
Universal Screening for Hepatitis Delta Virus (HDV) in Individuals Living with HIV/HBV Coinfection and HBV-related HCC
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Rate of positive anti-HDV
研究概览
简要总结
This is a territory-wide cross-sectional study of all individuals living with HIV/HBV coinfection and HBV-related HCC.
详细描述
Chronic hepatitis B virus (HBV) infection remains endemic in Hong Kong with an estimated prevalence of 6.2% in the recent Population Health Survey 2020-2022.1 The estimated prevalence of chronic HBV infection among individuals living with HIV is 8%.2 Yet, no data are available concerning the disease burden of hepatitis delta virus (HDV) among individuals living with HIV/HBV coinfection.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals with HIV infection, i.e. anti-HIV or HIV RNA positive; AND
- •Individuals with chronic hepatitis B, i.e. hepatitis B surface antigen (HBsAg) or HBV DNA positive for two times at least 6 months apart; AND
- •Aged 18 years old or above.
- •Written or verbal consent obtained
排除标准
- •Refusal to consent
- •Age < 18 years
结局指标
主要结局
Rate of positive anti-HDV
时间窗: at screening
Primary endpoint is seroprevalence rate of positive anti-HDV
次要结局
- Prevalence rate of detectable HDV RNA(at screening)
- Prevalence rate of compensated advanced chronic liver disease(at screening)
研究者
Grace Lai Hung Wong
Professor
Chinese University of Hong Kong
研究点 (1)
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