A Randomized Controlled Trial Comparing Postoperative Pain Following Total Abdominal Hysterectomy With General Anesthetic vs. Combined General and Spinal Anesthetic
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Total Morphine consumption
研究概览
简要总结
The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay following a total abdominal hysterectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •American Society of Anesthesiologists' (ASA) I and II patients undergoing elective Total Abdominal Hysterectomy at the Saskatoon City Hospital
- •Lower transverse abdominal incision
排除标准
- •BMI > 40
- •The TAH is treatment for cancer
- •A history of regular opioid use
- •Any medical condition that would make a spinal inadvisable,
- •An allergy or medical condition that would make it inadvisable to receive the drugs used in this study (eg. Peptic ulcer disease), or
- •If you will also be having a salpingo-oophorectomy).
研究组 & 干预措施
General Anesthesia
干预措施: General Anesthesia (control group) (Drug)
General Anesthesia + Spinal Anesthesia
干预措施: General Anesthesia + Spinal anesthesia combined (Drug)
结局指标
主要结局
Total Morphine consumption
时间窗: Post-operative day 2
The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.
Morphine consumption
时间窗: 1 day
The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward.
次要结局
- Pain score on the VAS(On post-operative day 2 at 22:00)
研究者
Jacelyn Larson
Faculty
University of Saskatchewan