Effect of initial treatment with tofogliflozin or metformin on pancreatic beta-cell function in subjects with drug-naive type 2 diabetes -A multicenter, prospective, open-label, parallel-group, randomized, comparative study

akamura Akinobu0 个研究点目标入组 70 人开始时间: 2023年5月9日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1) Age 20-90 years old
•2) HbA1c 6.5-9.0% and urine ketone negative
•3) Patients with type 2 diabetes who have not been taking any hypoglycemic agents more than 3 months
•4) Written informed consent

•1) History of anaphylaxis of tofogliflozin
•2) History of anaphylaxis of metformin
•3) History of lactic acidosis
•4) Unstable retinopathy
•5) Severe hepatic, renal, or cardiac dysfunction
•6) Pregnancy or possibly pregnant females
•7) Severe ketosis, diabetic coma
•8) Severe infection, surgery, serious trauma
•9) Deficiency of insulin secretion
•10) Dehydration or possibly dehydration
•11) Excessive alcohol consumption
•12) Malnutrition, starvation, debility, pituitary or adrenal insufficiency
•13) Inability to consume an appropriate diet
•14) Incompatibility with the trial for other reasons, as determined by the physician

发起方

akamura Akinobu