Correlation Between Radiculopathy And Quality Of Life In Patients With Chronic Lumbar Spondylosis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 132
- 主要终点
- life disability
研究概览
简要总结
This study will be conducted to answer the following question:
Is there a Correlation Between Lumbar Radiculopathy and Quality of Life in Patients with chronic lumbar spondylosis?
详细描述
Spondylosis is an age-related change of vertebrae and discs of the spine. These changes are often called degenerative disc disease and osteoarthritis. When this condition is in the lower back, it's called lumbar spondylosis.
Lumbar osteoarthritis, disc degeneration, degenerative disc disease, and spondylosis are some of the terms used to describe disc changes. In fact, the condition is called spondylosis. Whenever there is a degeneration co-occurrence in the disc, the lumbar spine, the formation of osteophytes and the associated changes in the nerves and the resulting symptoms of pain.Spinal osteoarthritis (OA) is a degenerative process defined radiologically by joint space narrowing, osteophytosis, subchondral sclerosis, and cyst formation.
Osteophytes included within this definition fall into one of the two primary clinical categories.
The first, spondylosis deforms describes bony outgrowths arising primarily along the anterior and lateral perimeters of the vertebral endplate apophyses. These hypertrophic changes are believed to develop at sites of stress to the annular ligament and most commonly occur at thoracic T9-10 and lumbar L3 levels.These conditions lead to nerve root compression, resulting in radiating pain down the leg, commonly referred to as sciatica. The impact of lumbar radiculopathy extends beyond pain, affecting muscle function and neuromuscular control. The involvement of nerve roots such as L4, L5, and S1 can particularly affect the muscles in the lower extremities, including the plantar flexor muscles, which are crucial for movements like walking, running, and maintaining balance
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 50 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patient diagnosed and referred from a physician
- •Patients suffered from lumbar spondylosis (L4: L5) with radiculopathy more than 3 months
- •Participants will be from both gender
- •Age will be ranged from 30 to
- •BMI of all participants ≤ 30 kg/m2
排除标准
- •Pregnant and breast-feeding women
- •Patients diagnosed with depression and anxiety
- •Patient who had undergone lumbar spine surgery
- •People with systemic illnesses or physical deformities
结局指标
主要结局
life disability
时间窗: up to one day
WHOQOL questionnaire will be used to assess life disability. it is defined as the individual's perception of their QoL. It consists of 24 questions which cover 4 categories plus 2 questions related to scale and health satisfaction. Each individual item of the WHOQOL-BRIEF is scored from 1 to 5 on a response scale, which is stipulated as a five-point ordinal scale. The scores are then transformed linearly to a 0-100-scale.
次要结局
- sciatic radiculopathy(up to one day)
- mechanosensitivity of the neuromeningeal structures within the vertebral canal(up to one day)
研究者
Mona Abdelmageed Ali
principale investigator: mona abdelmageed ali
Cairo University
