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临床试验/NCT05320458
NCT05320458Unknown不适用

Pulmonary Rehabılıtatıon After Chemotherapy In Patıents Wıth Non-Small Lung Cancer

Hasan Kalyoncu University1 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2022年5月2日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
11
试验地点
1
主要终点
Chance from baseline in posture analysis score

研究概览

简要总结

The aim of our study is to investigate the effects of pulmonary rehabilitation on respiratory tests and quality of life in patients with early and locally advanced NSCLC who received chemotherapy regardless of whether the investigators had undergone surgical treatment.

详细描述

Patients with lung cancer often have concomitant lung and heart comorbidities that limit their cancer treatment options. For example, in the last prevalence study that included patients with newly diagnosed lung cancer, 73% of whom were men and 53% were women, there was clinically significant COPD. This patient population has shortness of breath, decreased physical capacity, low muscle condiction, and poor exercise tolerance.

Pulmonary rehabilitation is an intervention that has a scientific basis and is used systematically, aiming to optimize individual daily functions and health-related quality of life in patients with morbidity due to chronic diseases measured by clinical or physiological methods.

The effectiveness of pulmonary rehabilitation is well known in the treatment of patients with COPD and in the perioperative lung transplant preparation period. Studies lead to a significant increase in preoperative pulmonary rehabilitation exercise capacity, dyspnea and health-related quality of life.

The aim of our study is to investigate the effects of pulmonary rehabilitation on respiratory tests and quality of life in patients with early and locally advanced NSCLC who received chemotherapy regardless of whether the investigators had undergone surgical treatment.

This study was conducted with outpatients who were diagnosed with small cell lung cancer between 2021-2022, who were approved by the oncologist and physical therapist to participate in a physiotherapy and rehabilitation program. Permission for the study was obtained from the Non-Interventional Local Ethics Committee (decision dated 20.11.2018 and numbered 2018/34). The study was conducted in accordance with the Helsinki Declaration of Patient Rights. Individuals were informed about the study and a written informed consent form was signed by the individuals who volunteered to participate.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Between the ages of 18-65, must be in remission.
  • Surgery, adjuvant chemotherapy and radiotherapy processes must be completed.

排除标准

  • Those with suspected pregnancy
  • Diabetes mellitus diagnosis
  • Patients in the metastatic period
  • Patients with a diagnosis of acute/chronic infection were excluded from the study.

结局指标

主要结局

Chance from baseline in posture analysis score

时间窗: 8 week

Posture score is going to be assess by posture analysis form to determine change from baseline.

次要结局

  • Physical Activity Level(8 week)

研究者

发起方
Hasan Kalyoncu University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kardelen HATIMOĞULLARI

physiotherapist

Hasan Kalyoncu University

研究点 (1)

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