NL-OMON27745已完成不适用
BONDS: Boosting Oxytocin after trauma: Neurobiology and the Development of Stress-related psychopathology .
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 220
研究概览
简要总结
Olff, M., W. Langeland, A. Witteveen, D. Denys, 2010. A psychobiological rationale for oxytocin in the treatment of posttraumatic stress disorder. CNS spectr., v. 15, no. 8, p. 522-30.
Frijling, J. L., van Zuiden, M., Koch, S. B., Nawijn, L., Goslings, J. C., Luitse, J. S., ... & Olff, M. (2014). Efficacy of oxytocin administration early after psychotrauma in preventing the development of PTSD: study protocol of a randomized controlled trial. BMC psychiatry, 14(1), 92.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Presentation at the Trauma Unit or Emergency Department after a potentially traumatic event, according to PTSD A1 criterion in the DSM-IV;
- •2. Trauma Screening Questionnaire (TSQ) ≥ 5, or Peritraumatic Distress Inventory (PDI) ≥ 17 between 24 and 72 hours after trauma exposure;
排除标准
- •1. Any severe or chronic systemic disease;
- •2. Current psychotic, bipolar, substance-related, severe personality disorder, or mental retardation;
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