Comparison of Priming Constituents in Patients Undergoing CPB Assisted Cardiac Surgery: HES 130/0.4 or Albumin 5%
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Post-operative bleeding and transfusion requirements
研究概览
简要总结
The purpose of the study is to determine which priming fluid is the safest for use for priming the heart-lung machine used during cardiopulmonary bypass for patients undergoing cardiac surgery. The fluids to be compared are albumin and voluven. A control group will receive only crystalloid.
详细描述
Project title:
Comparison of priming constituents in patients undergoing CPB assisted cardiac surgery: 6% HES 130/0.4 or Albumen 5%
Principal investigator:
Jo-Anne Marcoux M. Sc., CPC, CCP
Department:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 50 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing cardiopulmonary bypass assisted cardiac surgery
排除标准
- •emergencies and patients in renal failure or dialysis -
研究组 & 干预措施
Voluven or hydroethylstarch HES 130/0.4
Hydroethylstarch HES 130/0.4 used as part of the priming volume for the cardiopulmonary bypass circuit.
干预措施: Voluven (Other)
Crystalloid
Crystalloid will be used to prime the cardiopulmonary bypass circuit
干预措施: prime crystalloid (Other)
Human Albumin
Human albumin solution used as part of the priming volume for the cardiopulmonary bypass circuit.
干预措施: Human Albumin (Other)
结局指标
主要结局
Post-operative bleeding and transfusion requirements
时间窗: 24-48 hours post-operatively
Postoperative cardiac patients have chest tubes in place which drain any blood oozing from around the pericardial cavity. The chest tubes are attached to a blood collection apparatus which measures the amount of blood loss. Too much post-operative blood loss results in a transfusion requirement of red blood cells, plasma and/or platelets.
次要结局
- renal function, creatinine levels(24-48 hours post-operatively)
研究者
Jo-Anne Marcoux
Perfusionist M. Sc., CPC, CCP
University of Saskatchewan