NCT06531460招募中不适用
Effect of Perioperative Nutrition Enriched With Omega-3 on the Incidence of Infections in Oncologic Patients Following Lung Resection
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 310
- 试验地点
- 2
- 主要终点
- 30-day incidence infection
研究概览
简要总结
The aim of this study is to analyze the effect of enriched formula with omega-3 in the 30-day incidence infection and inflammatory response following lung resection surgery in lung cancer patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
盲法说明
Use of enteral formula enriched with omega-3 or standard not revealed for participants.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Lung cancer diagnosis
- •Elective surgery for lung resection schedule at least four days before surgery
- •Signed informed consent.
排除标准
- •Acute or chronic organ failure as hepatic or renal insufficiency
- •Patients with fish-allergy
- •History of any surgery within 3 months
- •Immunocompromised patients
结局指标
主要结局
30-day incidence infection
时间窗: 30-day incidence infection following lung resection in lung cancer patients.
Incidence of infectious complications after surgery diagnosed using any of these criteria: Infection of surgery wound confirmed by culture Infection confirmed by blood culture Pneumonia developed after surgery confirmed by chest x Ray.
次要结局
- Changes in Tumor Necrosis Factor Alpha (TNF-α)(At the beginning of nutritional therapy and at day-4 following surgery)
- Changes in prostaglandin E2(At the beginning of nutritional therapy and at day-4 following surgery)
- Hospital lenght of stay(During the hospital stay until 90-day)
- Changes in Interleukin-6(At the beginning of nutritional therapy and at day-4 following surgery)
- Number of participants with therapeutic antibiotics prescription(During the hospital stay until 30-day)
研究者
Ivan Armando Osuna Padilla
Clinical Nutrition Manager
National Institute of Respiratory Diseases, Mexico
研究点 (2)
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