NCT01228162已完成4 期
Influence of Muscle Relaxation With Rocuronium Bromide During General Anaesthesia on Muscle Trauma and Postoperative Analgetic Consumption in Patients With Total Hip Prosthesis Implantation
Klinikum Hildesheim GmbH1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2010年9月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- degree of muscle trauma
研究概览
简要总结
The researchers want to investigate the effects of muscle relaxation with rocuronium bromide during general anaesthesia on muscle trauma (serum CK, CRP) and postoperative analgesic consumption in patients with total hip prosthesis replacement (general vs. spinal anaesthesia).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient agreement
- •indication for total hip replacement
- •age 55 - 80 years
- •weight 65 - 95 kg
- •first intervention
- •ASA classification I - III
- •general and spinal anaesthesia possible in this patient
排除标准
- •a) neuromuscular diseases b) surgery with muscle trauma (within the last 3 months) c) permanent immobility d) intramuscular injections (within the last 4 weeks) e) medication with opioids f) medication with co-analgetics g) contraindications for general or spinal anaesthesia h) dementia, cognitive dysfunction or sleep apnea
结局指标
主要结局
degree of muscle trauma
时间窗: 24 hours
serum CK and CRP levels are measured
次要结局
- consumption of analgetics(3 days)
研究者
Dr. Jens Ebnet
MD
Klinikum Hildesheim GmbH
研究点 (1)
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