Peking Union Medical College Hospital
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Standardized uptake value of 68Ga-FAPI in ACC
研究概览
简要总结
This study was used to study the diagnostic value of 68Ga-FAPI, a novel fibroblast activating inhibitor, in metastatic adenoid cystic carcinoma（ACC）
详细描述
68Ga-FAPI is a positron labeled inhibitor of fibroblast activating protein, which has been widely used in malignant tumor imaging in recent years. Adenoid cystic carcinoma (ACC) is a rare epithelial malignant tumor, which usually originates from salivary glands. Its typical characteristics are long clinical course and high rate of distant metastasis. The purpose of this study was to investigate the clinical value of 68Ga Fapi pet/ct in metastatic adenoid cystic carcinoma.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with ACC suspected metastatic tumor,and being able to provide basic information and sign the written informed consent form
排除标准
- •claustrophobia, pregnancy, breastfeeding, kidney or liver failure, inability to fulfill the study
研究组 & 干预措施
68Ga-FAPI PET/CT
Imaging was performed 30-60 minutes after injection of 2-4mci 68Ga-FAPI tracer
干预措施: 68Ga-FAPI (Drug)
结局指标
主要结局
Standardized uptake value of 68Ga-FAPI in ACC
时间窗: 1 year
The maximum and mean standard uptake values (SUVmax and SUVmean) were measured in the background of lesion, liver, muscle and mediastinal blood pool, respectively.
次要结局
- lesions detected by 68Ga-FAPI PET/CT(1 year)