Evaluation of the Effects of Intrapulmonary Percussive Ventilation Using Functional Respiratory Imaging
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Lung function testing
研究概览
简要总结
In this study the invetigators seek an answer on the following hypothesis:
- What are the long term effects of an IPV treatment evaluated with classical outcome parameters? (FEV1, Raw)
- Is the possible effect noticeable on the novel technique and is this comparable with the classical outcome parameters?
详细描述
A Multicenter study conducted in university Hospital Antwerp (UZA) and ZNA Middelheim.
Tests are taken before and after one week IPV treatment. IPV is applied for 1 week during the physical therapy treatment of chronic obstructive pulmonary desease (COPD) patients admitted to the hospital for an excarebation. The IPV treatment is an additional treatment upon the standard treatment of the patients. The standard treatment consists out of existing drainage techniques to remove secretion out of the lungs by means of breathing control exercises. Patients are randomized into either the experimental group or the control group. The control group receives a standard physical therapy treatment without additional IPV treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted in the hospital for a acute exacerbation
- •Mild to severe COPD
排除标准
- •Ischemic / ventricular aritmic
- •Tracheotomise
- •Pneumothorax
- •Facial deformity
- •Recent nose, mouth or ear operations
- •Recent gastric operations.
- •Intubated
研究组 & 干预措施
Intrapulmonary percussive ventilation
IPV is applied for 1 week (once a day) during the physical therapy treatment of the patient
干预措施: intrapulmonary percussive ventilation (Device)
standard airwy claerance regime
The standard treatment consists out of existing drainage techniques to remove secretion out of the lungs by means of breathing control exercises
干预措施: standard treatment (Other)
结局指标
主要结局
Lung function testing
时间窗: baseline and after one week
(spirometric , bodybox en diffusion) Performed in the lung function laboratory according to ERS standards using Jaeger 5.1 device vital capacity (VC), FEV1, FEV1/VC, peak expiratory flow (PEF), MMEF 75/25, MEF 50, MEF 25, MIF 50, RV, total lung capacity (TLC), functionale residual capacity (FRC), resistance, spec resistance, TCO, alveolar volume (VA), TCO/VA, Maximal inspiratory pressure, Maximal expiratory pressure
次要结局
- functional respiratory imaging(at baseline and after one week)
研究者
Wilfried De Backer
Prof. Dr.
University Hospital, Antwerp