NCT05767697招募中不适用
Explore the Correlation of Genomics and Prognosis in Alimentary Tract Cancers
National Health Research Institutes, Taiwan2 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2020年4月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- Number of subjects who still survive at 1 year
研究概览
简要总结
This study aims to collect biospecimens and explore the correlation of genomics and prognosis in alimentary tract cancers.
详细描述
In this study, the investigators will collect clinical specimens of alimentary tract cancers and perform DNA and RNA analysis to identify genetic alterations for the development of a comprehensive somatic mutation databases and investigate their potential correlation with clinical, radiological and pathological variables. The genomics study included but not limited to target gene panel sequencing, whole exome sequencing, whole genome sequencing, bulk RNA sequencing, single cell RNA sequencing and metagenomics.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Able to sign the informed consent
- •Age >= 20
- •Histology proved pancreatic cancer, esophageal cancer, gastric cancer, hepatocellular carcinoma, cholangiocarcinoma, colorectal cancer
- •Agree to provide tumor/normal tissue including but not limited to surgical specimen, biopsy, cytology specimen, bile, urine or stool
- •Agree to receive blood sampling 20ml at first time and 10ml during each follow-up (total sampling amount no more than 30ml per month)
排除标准
- •Cannot cooperate with blood sampling
结局指标
主要结局
Number of subjects who still survive at 1 year
时间窗: 1 year
1 year overall survival rate
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
招募中
不适用
Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)Large Cell Neuroendocrine (NE) TumorsTreatment FailureBiomarkers / BloodBiomarkersImmunotherapySmall Cell Lung CancerNCT06717243Oncology Center of Biochemical Education And Research111
Unknown
不适用
Analysis of Prognostic and Predictive Genomic Signatures Using Archival Paraffin-embedded Tumor Specimens in Breast CancerBreast TumorNCT01247480National University Hospital, Singapore
Unknown
不适用
Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer CareMetastatic CancerAdvanced CancerCancers That Cannot be Treated With Curative IntentNCT04141397British Columbia Cancer Agency1,200
Unknown
不适用
Identification of Prognostic Gene Mutations in Biliary Tract Cancer Using Whole Genome SequencingBiliary Tract CancerNCT03718897Ji Kon Ryu100
招募中
不适用
A Global Study of the PETAL ConsortiumT-Cell and NK-Cell NeoplasmNCT06067347Massachusetts General Hospital1,200