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临床试验/NCT01258465
NCT01258465已完成不适用

Research in Autism: Parent Intervention

University of California, San Diego4 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2005年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
39
试验地点
4
主要终点
Mullen Scales of Early Learning

研究概览

简要总结

The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model. In one condition, randomly assigned children were provided with an intervention that typically results in acquisition of expressive words in a large percentage of children diagnosed as having autism, using a well-documented manualized intervention focused on verbal expressive communication only (Pivotal Response Training, PRT). In the other condi¬tion, randomly assigned children received a widely used intervention on the same social communication functions using a well-documented manualized augmentative system of intervention (Picture Exchange Communica¬tion System, PECS) that has been reported to produce verbal and nonverbal communication in large percentages of children diagnosed with autism. Children in the two conditions were compared for development of verbal and nonverbal communication, changes in disruptive behavior, changes in symptoms of autism, and general adaptive behavior gains. In addition, parent satisfaction and stress measures were gathered in order to assess the effects of each intervention on family functioning.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
24 Months 至 47 Months(Child)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of Autistic Disorder or At Risk of Autistic Disorder
  • Age 2-0 to 3-11 years of age
  • Use of fewer than 10 functional words at intake

排除标准

  • Primary diagnosis of mental retardation
  • Neurologic pathology (e.g., PKU, encephalitis, brain trauma)
  • Major sensory impairment

结局指标

主要结局

Mullen Scales of Early Learning

时间窗: 23 weeks with three months follow-up

次要结局

  • Vineland Adaptive Behavior Scales(23 weeks and 3 month follow up)

研究者

申办方类型
Other

研究点 (4)

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