NCT07040332招募中不适用
Pathogenesis and Inflammatory Phenotype of Allergic Bronchopulmonary Aspergillosis
Qianfoshan Hospital1 个研究点 分布在 1 个国家目标入组 140 人开始时间: 2025年5月10日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 140
- 试验地点
- 1
- 主要终点
- Total serum IgE
研究概览
简要总结
This study aims to reveal the immune and inflammatory regulatory molecular mechanisms related to the progression of allergic bronchopulmonary aspergillosis (ABPA), and to build a precision typing based on inflammation and identify the biomarkers of typing, and to explore the clinical outcomes of different inflammatory phenotypes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Meets the diagnostic criteria for allergic bronchopulmonary aspergillosis.
- •Meets the diagnostic criteria for fungal-sensitized asthma.
排除标准
- •Human immunodeficiency virus infection.
- •Malignant tumor.
- •Blood system disease.
- •autoimmune system disease.
- •History of pulmonary tuberculosis.
- •Patients with a history of smoking or still smoking.
- •Invasive pulmonary fungal disease.
- •Contraindications electronic bronchoscopy
结局指标
主要结局
Total serum IgE
时间窗: Up to 12 months
次要结局
- Aspergillus-specific IgE(Up to 12 months)
- Aspergillus-specific IgG(Up to 12 months)
研究者
Qian Qi
Dr.
Qianfoshan Hospital
研究点 (1)
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