The Becoming of Children With Doose Syndrome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- disease effects on the learning ability of children with doose syndrome
研究概览
简要总结
Doose syndrome is a rare epileptic syndrome that can lead to learning difficulties and a poor quality of life. The goal of this study is to evaluate the evolution of epilepsy and its consequences on cognitive development and learning issues in children with Doose syndrome.
详细描述
Doose syndrome is a rare epileptic syndrome beginning between ages two and five, characterized by myoclonic-astatic seizures which can be associated with myoclonic seizures, astatic seizures, absences and generalized tonic-clonic seizures. These seizures can be difficult to treat effectively and may lead to learning difficulties. During this study, parents of children with Doose syndrome will receive a questionnaire regarding learning disabilities, quality of life and epilepsy of their children.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 6 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •children with doose syndrome diagnosed between ages 1 and 6
- •normal development until onset of seizures
排除标准
- •unconfirmed diagnoses
- •abnormal diagnoses
- •abnormal psychomotor development before onset of seizures
- •cerebral MRI abnormalities
- •other child epileptic syndromes
结局指标
主要结局
disease effects on the learning ability of children with doose syndrome
时间窗: day of inclusion
disease effects on the learning ability of children with doose syndrome base on scholar informations
次要结局
- Evolution of epilepsy in children with doose syndrome based on pathological symptoms(day of inclusion)