Randomized interventiOn of Biventricular Pacemaker Function on ventrIcular Function Among Patients With mechaNical Circulatory Support Devices
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Peak Vo2
研究概览
简要总结
The primary reason the investigators are doing this study are to understand how the right side of the heart functions in heart failure patients with left ventricular assist devices (LVADs, or "mechanical hearts"). Second, the investigators are interested in understanding how different pacemaker settings influence function of the heart at rest and activity.
详细描述
Healthy individuals, as well as patients with advanced heart failure supported by LVADs, completed invasive hemodynamic analysis at rest and with exercise to characterize right-sided heart function at rest and with exercise during invasive cardiopulmonary exercise testing on upright cycle ergometry.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Peak Vo2
时间窗: 20 minutes
peak Vo2 measured by indirect calorimetry during cardiopulmonary exercise testing
Cardiac Output
时间窗: 20 minutes
cardiac output measured during invasive cardiopulmonary exercise testing.
次要结局
- Minute Ventilation(20 minutes)
- Blood Pressure(20 minutes)
- EES/EA(20 minutes)
- Tau(20 minutes)
- Stroke Work(20 minutes)
- Respiratory Exchange Ratio(20 minutes)