Biomarker Establishment for Superior Treatment of PTSD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 292
- 试验地点
- 2
- 主要终点
- Understanding the brain network function-neuroimaging and behavioral with Clinician-Administered PTSD Scale for DSM-5
研究概览
简要总结
The purpose of Biomarker Establishment for Superior Treatment of PTSD is to accelerate research on the discovery of biological, neurological and neuroimaging markers for Post- Traumatic Stress Disorder (PTSD). The investigators hope to validate and extend the network efficiency and verbal memory biomarker for PTSD. The investigators hope to learn whether there are pretreatment biological factors that can predict response to therapy. They want to do this by understanding the brain network function, relating EEG to functional magnetic resonance imaging, and application of network analysis tool.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of PTSD by VA clinicians and acceptance into PE or CPT treatment as part of the PCT
- •Veterans of any era
排除标准
- •MRI safety contraindications
- •Active, uncontrolled medical illness
- •Acute suicidality
- •Current substance dependence
- •Current use of thyroid medication or active hyper/hypothyroidism
- •Neurological disorder affecting the CNS Seg stroke, epilepsy, tumorW or penetrating head injury
- •Use of PRN within 48 hours of the MRI/EEG
结局指标
主要结局
Understanding the brain network function-neuroimaging and behavioral with Clinician-Administered PTSD Scale for DSM-5
时间窗: Approximately 3 months
We will be using CAPS 5
次要结局
未报告次要终点
研究者
Alan Schatzberg
Kenneth T. Norris, Jr. Professor of Psychiatry and Behavioral Sciences
Stanford University