Normal Range Study for Free Light Chains in Blood Among Identical or Fraternal Twins
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Free light chain reference range
研究概览
简要总结
The objective of this study is to recruit healthy adult identical and fraternal twins for the collection of one teaspoon of blood to be sent to the Clinical Lab at San Francisco General Hospital. The serum will be tested to determine the reference range for free light chains.
详细描述
Serum free light chains are used to assist in the diagnosis of multiple myeloma. The test measures kappa (K) and lambda (L) chains, and the calculation of the ratio of kappa to lambda (K/L). Previous studies have shown that the K/L ratio does not change over time (1 year). The hypothesis of this study is that healthy twins will have a K/L ratio that are close to each other in value, suggesting that this ratio is genetically linked.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
盲法说明
The participant will not be given the results of the free light chain result
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy subjects 18-80 years.
- •Must be an identical or fraternal twin (both must be recruited)
排除标准
- •Symptoms suggestive of multiple myeloma (e.g., renal insufficiency, anemia, bone pain) -
结局指标
主要结局
Free light chain reference range
时间窗: One month after the completion of the enrollment
Determination of the normal range for free light chains
次要结局
未报告次要终点