Magnification Endoscopy and Electronic Chromoendoscopy in Patients With Inflammatory Bowel Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Assessment of histopathological Inflammation
研究概览
简要总结
In this study the investigators aim to evaluate the ability of i-scan OE together with magnification endoscopy to detect and assess microscopic inflammation in patients with inflammator bowel diseases (IBD).
详细描述
In this study the investigators aim to evaluate the ability of i-scan OE together with magnification endoscopy to detect and assess microscopic inflammation in patients with inflammator bowel diseases. For this purpose, IBD patients will be prospectively enrolled and inflammatory changes will be assessed using optical magnification endoscopy in conjunction with optical chromoendoscopy. Endoscopic scoring of inflammatory changes in IBD patients will be done on a newly developed magnification score resulting as a consensus from experts in optical diagnosis and endoscopy in IBD patients. Results will be correlated against histopathology.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with established diagnosis of Inflammatory Bowel Diseases
- •Ability to provide written informed consent
- •Age 18 years and older
排除标准
- •poor bowel preparation
- •inability to provide written informed consent
结局指标
主要结局
Assessment of histopathological Inflammation
时间窗: 12 months
Histopathologic Inflammation will be assessed by grading inflammation of intestinal biopsies routinely obtained during colonoscopy on established pathological scores.
Assessment of endoscopic Inflammation
时间窗: 12 months
Endoscopic Inflammation will be determined and scored by assessement of the vascular and mucosal pattern under magnification endoscopy.
次要结局
未报告次要终点
研究者
Timo Rath
Professor of Endoscopy and Molecular Imaging
University of Erlangen-Nürnberg Medical School