NCT04377958已完成不适用
Development and Validation of a Serum Biomarker for the Diagnostic Work-up of Asthma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- KU Leuven
- 入组人数
- 117
- 主要终点
- Serum calprotectin
研究概览
简要总结
Serum samples of asthmatic patients will be screened for serum biomarkers
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 - 65 years
- •physician-diagnosed asthma
排除标准
- •No clear asthma phenotype
- •Presence of other pulmonary diseases (Chronic obstructive pulmonary disease, alfa-1-antitrypsine deficiency emphysema, Immunoglobulin E deficiency, allergic bronchopulmonary aspergillosis)
- •> 15 pack years
- •No sputum available
- •Respiratory infection
- •Other inflammatory diseases (Rheumatoid Arthritis, Colitis Ulcerosa)
结局指标
主要结局
Serum calprotectin
时间窗: Day 1
Serum Calprotectin (pg/ml) will be measured in serum samples using a U-plex assay
次要结局
- Sputum calprotectin(Day 1)
研究者
Tatjana Decaesteker
Principal Investigator
KU Leuven
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