A prospective, randomized, double blinded, controlled study for comparison of Dexmedetomidine, Lidocaine and Fentanyl in attenuation of Hemodynamic response to Laryngoscopy and Intubation in patients undergoing Cardiac Surgery at SMS Medical College, Jaipur

Department of Anaesthesiology1 个研究点分布在 1 个国家目标入组 90 人开始时间: 2022年2月6日最近更新: 2022年5月21日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 90
试验地点: 1
主要终点: Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Laryngoscopy and endotracheal intubation are associated with various hemodynamic changes due to sympathetic stimulation and to attenuate these responses is a major challenge for the anaesthesiologist. Hence, this study is designed to compare effects of intravenous Dexmedetomidine, Lidocaine and Fentanyl in Attenuation of Hemodynamic Response of Laryngoscopy and Intubation in patients undergoing Cardiac surgery.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 30.00 Year(s) 至 70.00 Year(s)（—）
性别: All

入选标准

•1.Informed Consent 2.Patients undergoing Elective Cardiac Surgery 3.Ejection Fraction >35% 4.ASA Grade 2 and 3 5.BMI<30.

排除标准

•1.Intubation Attempt lasting longer than 15s and any intubation related problem 2.Allergic Sensitivity to the research medications 3.Patients with hypotension(SBP<90 mmhg) 4.Bradycardia(HR<60/min) 5.Diabetes 6.Asthma 7.Pregnancy 8.Chronic Kidney and liver diseases 9.Long QT 10.Any Addiction.

结局指标

主要结局

Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure

时间窗: Before Intubation and 1,3,5,10 and 15 minutes post intubation

次要结局

Percentage of cases who experience side effects or complications(if any)(24 hours postoperation)

研究者

发起方

Department of Anaesthesiology

申办方类型

Government medical college

研究点 (1)

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