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临床试验/NCT04394039
NCT04394039已完成不适用

Effects of COVID-19-Related Self-isolation on Psychological Response to Different Outdoor Environments in Singapore - Before & After Brain and Behavior Study

National University of Singapore2 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2020年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
34
试验地点
2
主要终点
EEG power in alpha band

研究概览

简要总结

In this study it is aimed to investigate the difference between the brain response to different urban environments in Singapore before and after the COVID-19 pandemic. The datasets acquired from 34 healthy individuals as part of ongoing study "Effects of Landscape on the Brain" (IRB Ref #: S-18-352) will be used. These datasets consist of neurophysiological data recordings and behavioral self-reported measures and were collected before 20 of January 2020. The same experimental protocol would be followed, given that the data collection in the lab-setting would start after 7 th May 2020/whenever research activities are allowed to resume, and the outdoor sessions after the "circuit-breaker" period in Singapore is over.

详细描述

The aim is to explore the difference between pre and post COVID-19-related isolation on their perception of green and public spaces, as well as mood, neuroelectrical (EEG) and haemodynamic (fNIRS) response.

The hypothesi is that crowded, busy public spaces, such as experimental site near Chinatown MRT, may induce more patterns of brain activity related to stress, anxiety and aversive attitudes after COVID-19 as compared to before. Similarily, it is expected that green urban spaces, such as experimental site at Hortpark, perceived after COVID-19 can elicit more salutogenic effect of relaxation, positive emotions and attention restoration than before the pandemic.

This study will allow better understanding of the mental health consequences of unprecedented period of isolation at home and social distancing. The relationship between city residents and their living environment may change due to COVID-19 and it's very important to uncover the mental health implications of social distancing to prepare for potential future outbreaks through developing tools and solutions addressing specific issues. Finally, for the urban planning and design the study may highlight important trends in changing human perception of space and redefine the concept of a "healthy city".

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Sequential
主要目的
Supportive Care
盲法
None

盲法说明

participants do not know the hypothesis of the study, other people cannot influence the brainwave reaction

入排标准

年龄范围
21 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age of 21 to 75
  • Right-handed only

排除标准

  • left-handed
  • serious visual or auditory impairment
  • Major neurological disorders e.g. epilepsy, stroke
  • Any form of cancer
  • Major heart diseases: e.g. ischemic heart disease
  • Major lung diseases: e.g. chronic obstructive pulmonary disorder.
  • Major liver disease e.g. liver failure
  • Major kidney disease e.g. kidney failure

结局指标

主要结局

EEG power in alpha band

时间窗: 5 minutes

predictor of positive affect and positive mental health outcomes, measured with EEG

EEG power in beta band

时间窗: 5 minutes

more beta in the right temporal lobes associated with stimuli-driven attention, measured with EEG

fNIRS haemodynamics

时间窗: 5 minutes

decreased oxy-hemoglobin in the frontal part of the brain indicates more relaxation

次要结局

  • landscape preference measured with self-assessment manikin scale(30 minutes)
  • Profile of mood states(30 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Agnieszka Olszewska-Guizzo

Dr.

National University of Singapore

研究点 (2)

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